- Venue National Theatre - Lyttelton Theatre, London
- Performance dates Booking to 7 October 2023
- Running time 1 hour 40 minutes (no interval)
★★★★★ “Tender, thrilling and elegantly brutal” – The Stage
A major new revival of acclaimed play The Effect by Lucy Prebble (Succession) is now playing at the National Theatre starring Paapa Essiedu and Taylor Russell.
Lucy Prebble’s funny and intimate examination of love and ethics is directed by Jamie Lloyd (Cyrano de Bergerac, A Doll’s House).
The cast includes rising stars Paapa Essiedu (I May Destroy You, The Capture) as Tristan and Taylor Russell (Bones and All, Lost in Space) as Connie.
The Effect is playing in the Lyttelton theatre at the National Theatre to 7 October 2023.
Hearts and minds racing, Connie and Tristan are falling for each other fast. But is their sudden and intoxicating chemistry real, or a side effect of a new antidepressant? As two
young volunteers in a clinical drug trial, their romance poses startling dilemmas for the supervising doctors.
Videos & Photos
Performance Information
Check booking calendar for full details
- Evenings
- Monday
- Tuesday
- Wednesday
- Thursday
- Friday
- Saturday
- Matinees
- Wednesday
- Saturday
- Group Bookings For groups of 10+ enquire here
Stars and Creatives
Who is in the cast of The Effect?
Paapa Essiedu stars as Tristan, Taylor Russell as Connie, Kobna Holdbrook-Smith as Dr Toby Sealey, and Michele Austin as Dr Lorna James.
Other cast include Shereener Browne, Valentine Hanson, Mara Huf, and Joseph Langdon.

Who are the creative team of The Effect?
Directed by Jamie Lloyd with set and costume designer Soutra Gilmour, lighting designer Jon Clark, composer Michael ‘Mikey J’ Asante, sound designer George Dennis, movement directors Sarah Golding and Yukiko Masui (SAY), , fight director Kate Waters, intimacy co-ordinator Ingrid Mackinnon and casting director Alastair Coomer CDG.
Important Notes
Notes:
Latecomers cannot be admitted and there is no re-admittance to the theatre during this performance. The running time is 1 hour and 40 minutes, without an interval.
This production contains strong language and adult themes. There are strobe/flashing lights, smoke and haze effects, with some loud music.
Some scenes include sexual content, physical aggression, depictions of seizures and references to depression, anxiety and suicide.
Venue Information
National Theatre - Lyttelton Theatre , Upper Ground, London, SE1 9PX
Nearest Tube or Train: Waterloo (Jubilee line, Northern line, Bakerloo line)
Nearest Buses: 1, 4, 26, 59, 68, 76, 139, 168, 171, 172, 176, 188, 243, 341, 521, X68, RV1
Critics' reviews of The Effect
★★★★★ "Tender, thrilling and elegantly brutal" - The Stage
★★★★ "Lucy Prebble’s intense and intoxicating encounter" - The Guardian
★★★★ "A fiery play that explores and questions 'lab-made' love" - The Telegraph
★★★★ "Paapa Essiedu is all compelling, shambling, vulnerable charm" - The Independent
★★★★ "A mind-bending experience" - The Evening Standard













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